Pharmacology (from Greek φάρμακον, pharmakon, "poison" in classic Greek; "drug" in modern Greek; and -λογία, -logia"study of", "knowledge of") is the branch of medicine and biology concerned with the study of drug action.[1] More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. The former studies the effects of the drugs on biological systems, and the latter the effects of biological systems on the drugs. In broad terms, pharmacodynamics discusses the interactions of chemicals with biological receptors, andpharmacokinetics discusses the absorption, distribution, metabolism, and excretion of chemicals from the biological systems. Pharmacology is not synonymous with pharmacy and the two terms are frequently confused. Pharmacology deals with how drugs interact within biological systems to affect function. It is the study of drugs, of the reactions of the body and drug on each other, the sources of drugs, their nature, and their properties. In contrast, pharmacy is a biomedical science concerned with application of the principals learned from pharmacology in its clinical settings; whether it be in a dispensing or clinical care role. In either field, the primary contrast between the two are their distinctions between direct-patient care, for pharmacy practice, and the science-oriented field, driven by pharmacology.Dioscorides' De Materia Medica is often said to be the oldest and most valuable work in the history of pharmacology. The origins of clinical pharmacology date back to theMiddle Ages in Avicenna's The Canon of Medicine, Peter of Spain's Commentary on Isaac, and John of St Amand's Commentary on the Antedotary of Nicholas. Clinical pharmacology owes much of its foundation to the work of William Withering. Pharmacology as a scientific discipline did not further advance until the mid-19th century amid the great biomedical resurgence of that period. Before the second half of the nineteenth century, the remarkable potency and specificity of the actions of drugs such as morphine,quinine and digitalis were explained vaguely and with reference to extraordinary chemical powers and affinities to certain organs or tissues. The first pharmacology department was set up by Rudolf Buchheim in 1847, in recognition of the need to understand how therapeutic drugs and poisons produced their effects.
Early pharmacologists focused on natural substances, mainly plant extracts. Pharmacology developed in the 19th century as a biomedical science that applied the principles of scientific experimentation to therapeutic contexts.
Divisions
Clinical pharmacology
The medical field of medication effects on humans and animals.
Neuropharmacology
Effects of medication on nervous system functioning.
Psychopharmacology
Effects of medication on the brain; observing changed behaviors of the body and read the effect of drugs on the human brain.Pharmacogenetics
Clinical testing of genetic variation that gives rise to differing response to drugs.
Pharmacogenomics
Application of genomic technologies to new drug discovery and further characterization of older drugs.
Pharmacoepidemiology
Study of effects of drugs in large numbers of people.
Toxicology
Study of harmful or toxic effects of drugs.
Theoretical pharmacology
Study of metrics in pharmacology.
Posology
How medicines are dosed. It also depends upon various factors like age, climate, weight, sex, and so on.
Pharmacognosy
A branch of pharmacology dealing especially with the composition, use, and development of medicinal substances of biological origin and especially medicinal substances obtained from plants also known as deriving medicines from plants
Behavioral pharmacology
Behavioral pharmacology, also referred to as psychopharmacology, is an interdisciplinary field which studies behavioral effects of psychoactive drugs. It incorporates approaches and techniques from neuropharmacology, animal behavior and behavioral neuroscience, and is interested in the behavioral and neurobiological mechanisms of action of psychoactive drugs. Another goal of behavioral pharmacology is to develop animal behavioral models to screen chemical compounds with therapeutic potentials. People in this field (called behavioral pharmacologists) typically use small animals (e.g. rodents) to study psychotherapeutic drugs such as antipsychotics, antidepressants and anxiolytics, and drugs of abuse such as nicotine, cocaine, methamphetamine, etc
Environmental pharmacology
Environmental pharmacology is a new discipline. Focus is being given to understand Gene–environment interaction, drug-environment interaction and toxin-environment interaction. There is a close collaboration between the Environmental science and Medical community in addressing these issues. It is recognised that healthcare can itself be a cause of Environmental damage as well as its remediation. Human health and ecology is intimately related. Demand for more pharmaceutical products is destroying countless species of animals and plants, placing the public at risk. The entry of chemicals and drugs into the Aquatic ecosystem is a more serious concern today. In addition, the production of some Illegal drugs pollutes drinking water supply by releasing carcinogens. The pharmaceutical industry is encouraged to pay greater attention to the environmental impact of its products. More and more biodegradability of drugs are needed. It means environment friendly drugs could be designed. General standards for discharge of environment pollutants is implemented strictly and environmental impact assessment is checked frequently by health and other concerned regulators. Today, inEnvironmental Pharmacology, the topics which are covered includes Pharmacoenvironmentology
.jpg)
Posts
